HomeCOVID-19Signals of Alzheimer Found in Brains of Covid-19 Patients, New Research Discovers

Signals of Alzheimer Found in Brains of Covid-19 Patients, New Research Discovers

According to new research, Alzheimer’s-like signaling has been found in the brains of COVID-19 patients.

The study was published in Alzheimer association under the title “Alzheimer’s-like signaling in brains of COVID-19 patients.”.

Researchers such as Steve Reiken, Leah Sittenfeld, Haikel Dridi, Yang Liu, Xiaoping Liu, and Andrew R. Marks made the study.

Researchers found a link between SARS-CoV-2 infection and activation of TGF-β signaling and oxidative stress in the study, Alz Journals reported.

The researchers found that in COVID-19 patients, the neuropathological pathways that cause tau hyperphosphorylation, typically associated with Alzheimer’s disease (AD), are also activated.

Read More: A Woman Infected Her Completely Vaccinated Elderly Companion With Covid-19, Later Succumbed to Death.

RyR2 was found to exhibit a “leaky” phenotype in COVID-19 brains, which contributes to cognitive and behavioral deficits.

Based on the results of the study, SARS-CoV-2 infection appears to activate inflammatory signaling pathways and oxidative stress pathways, resulting in tau hyperphosphorylation, though amyloid precursor protein (APP) processing appears normal in the cortex and cerebellum of COVID-19 patients.

In their study, the researchers suggested that the altered dynamics of cellular calcium resulting from leaky RyR2 in COVID-19 brains are also associated with neuropathological pathways in AD brains.

NATE GARTRELL
NATE GARTRELLhttps://theeastcountygazette.com/
NATE GARTRELL is an author at TheEastCountyGazette.com, a publication in the East County region of San Diego County. He has been writing for the Gazette since 2012 and writes on many different topics including politics, business, health care and more.
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